Born in Leuven on 25 July 1956, Patrick de Radiguès first made his name as an endurance motorcycle racer, with a Bol d'Or win and a second place in the endurance world championship.
He turned to sailing at 36. He finished third in the Transat Jacques Vabre aboard La Novia with Yves Le Cornec, then fifth in the 1995 Transat Québec-Saint-Malo on the same boat.
He took part in the 1996-1997 Vendée Globe, where he was unclassified, and in the 2000-2001 Vendée Globe aboard La Libre Belgique, which he abandoned. In 2001 he was co-skipper to Jean-Luc Nélias on the trimaran Belgacom. His brother Didier de Radiguès is also a motorcycle racer.